Rev Esp Quimioter 2017; 30(1):1-8
Fluoroquinolones: Non-antibacterial properties
SOCORRO LEYVA-RAMOS, HIRAM HERNÁNDEZ-LÓPEZ
Fluoroquinolones are a class of well-established chemotherapeutic agents with a potent biological activity being the structure of 4-quinolone-3-carboxilic acids privileged because it contains different sites for functionalization allowing expand its use in clinical practice for their antifungal, antiviral and anticancer activities. Quinolones structural changes have resulted in a first, second, third and fourth generation of drugs so it is advisable to continue modifying existing structures in new ways to generate compounds with desirable biological and pharmacological properties.
Rev Esp Quimioter 2017; 30(1):1-8 [pdf]