Seroprevalence of antibodies against measles virus in Galicia: trends during the last ten years depending on age and sex
JOSÉ JAVIER COSTA-ALCALDE, ROCÍO TRASTOY-PENA, GEMA BARBEITO-CASTIÑEIRAS, DANIEL NAVARRO DE LA CRUZ, BEATRIZ MEJUTO, ANTONIO AGUILERA
Objectives. In 1998, the Europe Region of the World Health Organization set the goal of eliminating measles. In this study, the prevalence of immunity against measles virus in the population of the health area of Santiago de Compostela was analyzed based on data obtained between 2008-2018.
Methods. A total of 7,150 different patients were studied and divided into groups according to their year of birth: 2010-2017, 2000-2009, 1990-1999, 1980-1989, 1953-1979 and <1953. The serum determination of IgG against measles virus was performed using a commercialized chemiluminescent immunoassay.
Results. A minimum (76%) was observed for measles virus protection rates in those born between 1990-1999. By age group it was seen that in all groups the women presented a higher percentage of antibodies against measles. In a logistic regression model with year of birth and sex, an odds ratio of 1.06 (p<0.001) was obtained for the year of birth and of 0.82 (p=0.0013) for sex.
Conclusions. It was observed lower seroprevalences from the implantation of the vaccine and a more pronounced change during the implantation period. From the vaccination plan for measles of the year 2000 in Galicia, the rates of protection against the virus of the measles have been increasing in our area. Although there is a greater proportion of women protected against men, these differences are small.
Rev Esp Quimioter 2020; 33(2): 116-121 [Texto completo PDF]