Rev Esp Quimioter 2021; 34(3):185-192

Role of cefditoren in the treatment of community skin and soft tissue infections: revisiting the evidence

MARTA DAFNE CABAÑERO-NAVALÓN, VÍCTOR GARCÍA-BUSTOS, MIGUEL SALAVERT LLETÍ

Published: 24 May 2021

http://www.doi.org/10.37201/req/063.2021

Cefditoren pivoxil is a third-generation oral cephalosporin with extended spectrum against Gram-negative, Gram-positive, and several anaerobic microorganisms, including those frequently implicated in skin and soft tissue infections (SSTI). Despite the fact that there are no approved breakpoint criteria for cefditoren susceptibility, many pharmacokinetic and pharmacodynamic studies reassert cefditoren as a good oral antibiotic for the treatment of SSTI. Regarding patients with SSTI, including those infections caused by Staphylococcus aureus y Streptococcus pyogenes, cefditoren showed high cure rates when compared to other oral cephalosporins.

Rev Esp Quimioter 2021; 34(3):185-192 [Full-text PDF]