Rev Esp Quimioter 2022;35(Suppl.3):6-9

Management of hyperinflammation in COVID-19 patients

BORJA SUBERVIOLA, ELENA CUENCA FITO

Published: 24 October 2022

http://www.doi.org/10.37201/req/s03.02.2022

In response to SARS-CoV-2 infection, the immune system physiologically upregulates to try to clear the virus from the body; failure to compensate for this inflammatory response with an anti-inflammatory response leads to dysregulation of the immune system that ultimately leads to a situation of uncontrolled hyperinflammation called cytokine storm. This cytokine storm can cause ARDS or multi-organ failure leading to patient death. This review exposes the different mechanisms of the inflammatory response in COVID-19 infection and the therapeutic options to treat this process.

Rev Esp Quimioter 2022; 35(Suppl.3):6-9 [Full-text PDF]