Rev Esp Quimioter 2017; 30(6): 429-435

Evolution of the Complexity Index of the antiretroviral therapy in HIV+ patients in a real life clinical practice

MERCEDES MANZANO-GARCÍA, AGUAS ROBUSTILLO-CORTÉS, CARMEN VICTORIA ALMEIDA-GONZÁLEZ, RAMÓN MORILLO-VERDUGO

Introduction. HIV infection has been one of the biggest successes in the healthcare world, mainly due to the appearance of antiretroviral treatment (ART). The complexity of this type of treatment has been one of the decisive factors in the follow-up of these patients.
Methods. An analytical, unicentric, retrospective observational study. We included all patients older than 18 years of age who were diagnosed with HIV who received ART in follow-up for the consultation of pharmaceutical pathology care during the year 2015. The evolution of the complexity index of ART over time and its relation with adherence to ART and concomitant treatment.
Results. A total of 619 patients were included in the study with a mean age of 47.03 ± 10.18 years. There was a reduction in CI over the years, with a significant decrease in the year 2013 and in 2015. The results obtained after the analysis of the secondary variables showed a significant relation between the adhesion to the ART and the CI of this. Patients have a lower CI (3.5) than non-adherent patients (4.25). (P = 0.003).
Conclusions. The complexity of ART is being reduced mainly by new treatment strategies and the increasing appearance of pharmaceutical coformulations. A reduction in the complexity of ART assumes a better adherence to it.

Rev Esp Quimioter 2017; 30(6): 429-435 [Texto completo PDF]