Rev Esp Quimioter 2019; 32(2): 98-113

Austrian syndrome: A rare manifestation of invasive pneumococcal disease. A case report and bibliographic review

MARTA RODRÍGUEZ NOGUÉ, IGNACIO GÓMEZ ARRAIZ, GEMA ARA MARTÍN, Mª MAR FRAJ VALLE, ANTONIO GÓMEZ PELIGROS

The Austrian syndrome is a pathology caused by disseminated Streptococcus pneumoniae infection and characterized for the triad of pneumonia, endocarditis and meningitis. It has an estimated incidence of 0.9-7.8 cases per ten millions people each year, and a mortality of 32%. Alcohol abuse, as the main risk factor, appears only in four out of ten patients. Moreover, 14% of patientes do not have any risk factor. Two out of three patients are males and it occurs in the middle aged of life. It is more frequently on native valve, aortic valve is injured in the half of the cases. Severe regurgitation occurs in two per three patients. Appropriate antimicrobial treatment and early endocarditis surgery decrease mortality. It is possible that Austrian syndrome epidemiology is changing by the introduction of 13-valent pneumococcal conjugated vaccine in the children´s calendar.

Rev Esp Quimioter 2019; 32(2): 98-113 [Texto completo PDF]