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Rev Esp Quimioter 2022; 35(2):157-164

Prevalence of SARS-CoV-2 infection during the first wave of the pandemic among health and non-health personnel of the General Hospital of Segovia, Castilla y León

CARLOS AVELLANEDA MARTÍNEZ, JULIO CÉSAR SANTOS PASTOR, ISABEL MARÍA MARCOS SÁNCHEZ, AINHOA NARROS GIMÉNEZ, MARÍA GUTIÉRREZ DE ANTÓN, PABLO ALONSO CHACÓN

Published: 17 January 2022

http://www.doi.org/10.37201/req/094.2021

Introduction. Health and non-health workers (H&NH-W) in a hospital are more exposed to SARS-CoV-2 infection than the general population. We studied the prevalence of this infection in these workers of Segovia´s Hospital after the first epidemic wave.
Material and methods. Monocentric, observational, cross-sectional study, carried out between April 29 and May 14, 2020. The infection was diagnosed by capillary immunochromatography test for IgG and / or IgM antibodies, or PCR. Work, health, and exposure variables were studied.
Results. A total of 1,335 H&NH-W participated in the study out of a total of 1,667 (80.1%), 79.3% women, with a mean age of 47.3 years, and 47.1 for men. The prevalence of infected was 21.95%, 24.7% asymptomatic. Age presented a significant OR of 1.02/year. Exposure outside of work increased the prevalence by 16.8%. The continued use of Personal Protective Equipment (PPE) and the administration of nebulizations presented an OR of 0.54 and 0.46 respectively. The symptoms associated with the highest prevalence were anosmia (OR 9.31), ageusia (OR 3.05), and fever (OR 1.94). Today, about 75% of H&NH-W were infected in the first wave.
Conclusions. The prevalence is higher among healthcare workers than the population they serve. Age is associated with a higher prevalence of infection. Almost a quarter of those infected were asymptomatic. The continuous use of PPE was associated with a lower prevalence, for that the administration of nebulisations could be safe. The symptoms with the greatest association were fever, anosmia, and ageusia.

Rev Esp Quimioter 2022; 35(2):157-164 [Texto completo PDF]


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Rev Esp Quimioter 2022; 35(2):131-156

Past and future of HIV infection. A document based on expert opinion

EMILIO BOUZA, JOSÉ RAMÓN ARRIBAS, BELÉN ALEJOS, JOSÉ IGNACIO BERNARDINO, MAYE COIRAS, PEP COLL, JORGE DEL ROMERO, MARÍA JOSÉ FUSTER, MIGUEL GÓRGOLAS, ALIPIO GUTIÉRREZ, DIEGO GRACIA, VICTORIA HERNANDO, JAVIER MARTÍNEZ-PICADO, JOSÉ MANUEL MARTÍNEZ SESMERO, ESTEBAN MARTÍNEZ, SANTIAGO MORENO, BEATRIZ MOTHE, MARIA LUISA NAVARRO, DANIEL PODZAMCZER, FEDERICO PULIDO, JOSÉ TOMÁS RAMOS, EZEQUIEL RUIZ-MATEOS, INÉS SUÁREZ GARCÍA, ESTEBAN PALOMO

Published: 12 January 2022

http://www.doi.org/10.37201/req/083.2021

HIV infection is now almost 40 years old. In this time, along with the catastrophe and tragedy that it has entailed, it has also represented the capacity of modern society to take on a challenge of this magnitude and to transform an almost uniformly lethal disease into a chronic illness, compatible with a practically normal personal and relationship life. This anniversary seemed an ideal moment to pause and reflect on the future of HIV infection, the challenges that remain to be addressed and the prospects for the immediate future. This reflection has to go beyond merely technical approaches, by specialized professionals, to also address social and ethical aspects. For this reason, the Health Sciences Foundation convened a group of experts in different aspects of this disease to discuss a series of questions that seemed pertinent to all those present. Each question was presented by one of the participants and discussed by the group. The document we offer is the result of this reflection.

Rev Esp Quimioter 2022; 35(2):131-156 [Full-text PDF]


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Rev Esp Quimioter 2022; 35(1):80-83

Impact of SARS-COV-2 on the diagnosis of community bacteremia in a tertiary hospital

SARAY MORMENEO BAYO, MIGUEL MORENO HIJAZO, MARÍA PILAR PALACIÁN RUÍZ, MARÍA CRUZ VILLUENDAS USÓN

Published: 5 January 2022

http://www.doi.org/10.37201/req/104.2021

Objective. We carry out an analysis of the bacteremia diagnosed in the Emergency Department during 2020, coinciding with the period of the pandemic.
Method. We performed a retrospective analysis from March 4, 2020 to December 31, 2020.
Results. The number of patients who went to the Emergency Department during the study period and the number of extracted blood cultures decreased by 46.79% and 35.7% compared to the same period in 2019 (p <0.05). 320 bacteremia occurred while 507 occurred in 2019, assuming a decrease of 36.8% (p <0.05). The positivity rate of blood cultures was 7.09% in 2020 and 7.23% in 2019 and the contamination rate was 7.07 % in 2020 and 5.67% in 2019. The most frequently isolated microorganism was Escherichia coli, followed by Staphylococcus aureus and Klebsiella pneumoniae. A 6.62% of the isolated E. coli were carriers of extended-spectrum beta-lactamases (ESBL). The percentage of methicillin-resistant S. aureus was 12.9 % and that of K. pneumoniae ESBL was 11.54%.
Conclusion. During the SARS-CoV-2 pandemic there has been a decrease in the number of bacteremia diagnoses, it is possible that attention was focused especially on COVID, forgetting other diseases, such as bacteremia.

Rev Esp Quimioter 2022; 35(1):80-83 [Texto completo PDF]


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