(Pneumococcal septic arthritis in a patient with mixed connective tissue disease)
JORGE LIGERO LÓPEZ, MARÍA CONCEPCIÓN GÓMEZ CRIADO
Published: 15 April 2020
http://www.doi.org/10.37201/req/004.2020
LETTER TO THE EDITOR
Rev Esp Quimioter 2020; 33(3): 221-222 [Texto completo PDF]
BELÉN RODRÍGUEZ DE CASTRO, CRISTINA MARTÍNEZ-MÚGICA BARBOSA, RUBÉN PAMPÍN SÁNCHEZ, BEATRIZ FERNÁNDEZ GONZÁLEZ, FRANCISCO JAVIER BARBAZÁN VÁZQUEZ, CARLOS APARICIO CARREÑO
Published: 15 April 2020
http://www.doi.org/10.37201/req/026.2020
Objective. Evaluation of the effectiveness of a standard dose of cefalozin 2 grams for surgical site infection (SSI) prevention in obese patients compared to non-obese patients. There is no still controversy surrounding which is the best dosage of this antibiotic in obese patients for surgical prophylaxis.
Material and methods. Retrospective review of men who received prophylactic cefazolin between January 1st, 2019 and June 30th, 2019 in a traumatology department of a university hospital. Patients were stratified into 2 groups: obese (≥ 100 kg and body mass index (BMI)> 30 kg / m2) and non-obese. Patients without a 90 days follow-up after surgery and/or with an active infection at the time of surgery and/or treated with immunosuppressants were excluded. Demographic data, height, real weight, smoking, diabetes, concomitant use of immunosuppressants, surgery data and presence of infection until day 90 were collected.
Results. A total of 57 patients underwent traumatic surgery with prophylactic cefazolin, 26 non-obese and 23 obese, were studied. Both groups presented statistically significant differences in weight, BMI and post-surgery use of cefazolin. No significant differences were observed in the other variables. Two obese (8.7%) and two non-obese (7.7%) patients developed SSIs after 63 days post-surgery on average, following the difference between the groups being statistically non-significant.
Conclusion. This study shows that there is no significant difference in SSI with a standard prophylactic dose of two grams of cefazolin between obese and non-obese patients.
Rev Esp Quimioter 2020; April 15 [Texto completo PDF]
(Pseudomonas stutzeri prosthetic joint infection: a therapeutic challenge associated with multiple severe complications)
DAVID ALONSO MENCHÉN, JOSÉ MARÍA BARBERO ALLENDE, JAVIER BALSA VÁZQUEZ, CARLOS IGNACIO JACOB GARCÍA-ASENJO, GUIOMAR HERNÁNDEZ GARCÍA, REBECA FONT GONZÁLEZ
Published: 13 April 2020
http://www.doi.org/10.37201/req/103.2019
LETTER TO THE EDITOR
Rev Esp Quimioter 2020; 33(3): 218-220 [Texto completo PDF]
(Tuberculosis infection in an unusual location)
ANA BETRÁN, Mª JOSÉ LAVILLA, ROSA ROSELLÓ, LUIS TORRES
Published: 10 April 2020
http://www.doi.org/10.37201/req/093.2019
LETTER TO THE EDITOR
Rev Esp Quimioter 2020; 33(3): 214-215 [Texto completo PDF]
(Liver involvement in listeriosis? Think of a hepatitis E virus coinfection)
IRENE SÁNCHEZ-MIRANDA ROMÁN, LAURA SUÁREZ-HORMIGA, MARÍA-ARACELI HERNÁNDEZ-BETANCOR, JOSÉ-LUIS PÉREZ-ARELLANO
Published: 3 April 2020
http://www.doi.org/10.37201/req/092.2019
LETTER TO THE EDITOR
Rev Esp Quimioter 2020; 33(3): 212-213 [Texto completo PDF]
JORDI REINA
Published: 1 April 2020
http://www.doi.org/10.37201/req/028.2020
On December 31, 2019 a pneumonia outbreak caused by a new coronavirus (SARS-CoV-2) was detected in the city of Wuhan (China). Due to the high capacity of diffusion and human infection it has become a new zoonotic pandemic. The absence of a vaccine has determined the search for antiviral drugs with the capacity to inhibit the replication of the new virus. Among them, remdesivir, an analogue of adenosine, is what seems to have a more promising future. This drug has shown in vitro and in animals a high capacity to block infection and viral replication with attainable concentrations in human plasma. Although all studies have been carried out with SARS-CoV and MERS-CoV, it seems that by virological and functional analogy, remdesivir is one of the few antiviral drugs with proven efficacy.However, studies and clinical trials in humans are required to know the result of their application in them.
Rev Esp Quimioter 2020; 33(3): 176-179 [Texto completo PDF]
MARIO GIL-CONESA, JUAN ANTONIO DEL-MORAL-LUQUE, NIEVES CLIMENT-MARTÍNEZ, ALBERTO DELGADO-IRIBARREN, RITA RIERA-PÉREZ, CARLOS MARTÍN-CABALLERO, CAROLINA CAMPELLO-GUTIÉRREZ, MANUEL DURÁN-POVEDA, GIL RODRÍGUEZ-CARAVACA, ÁNGEL GIL-DE-MIGUEL, DIEGO RODRÍGUEZ-VILLAR
Published: 31 March 2020
http://www.doi.org/10.37201/req/098.2019
Objectives. Health care-related infections are a public health problem, among them surgical site infection (SSI) are the most frequent in hospitals. The objetive of this study was to assess the effect of the compliance to antibiotic prophylaxis protocol on the incidence of surgical site infection in hysterectomized patients.
Material and methods. A prospective cohort study was carried out between October 2009 and December 2018. The incidence of SSI was studied after a maximum period of 30 days from the moment of surgery. The degree of adequacy of antibiotic prophylaxis in hysterectomy and the effect of its inadequacy on the incidence of infection was evaluated using relative risk (RR) adjusted with a logistic regression model.
Results. A total of 1,025 interventions were studied in 1,022 women. The cumulative incidence of SSI was 2,1% (n = 22). The most frequent etiology of infection was Escherichia coli (23.1%) and Proteus mirabilis (23.1%). Antibiotic prophylaxis was indicated in 1,014 interventions (98.9%) being administered in 1,009 of them (99.5%). The adherence to the protocol was 92,5%. The main cause of non-compliance was the time of onset (40.9%), followed by the choice of the antibiotic (35.2%). The effect of inadequate prophylaxis on the incidence of infection was RR = 0.9; 95% CI 0.2-3.9; p> 0.05.
Conclusions. The adequacy of antibiotic prophylaxis was very high, with a low incidence of surgical site infection. No association was found between adequacy of prophylaxis and incidence of infection in hysterectomy. The continuous improvement of epidemiological surveillance in gynecology should be emphasized.
Rev Esp Quimioter 2020; 33(3): 180-186 [Texto completo PDF]
(Detection of Streptococcus pyogenes in throat swab samples using antigen detection technique)
ISABEL CASANOVAS MORENO-TORRES, GEMMA JIMÉNEZ GUERRA, CARLA FORONDA GARCÍA-HIDALGO, MARÍA LUISA SERRANO GARCÍA
http://www.doi.org/10.37201/req/078.2019
LETTER TO THE EDITOR
Rev Esp Quimioter 2020; 33(2): 137-138 [Texto completo PDF]
(Dalbavancin combined with linezolid in prosthetic-hip infection)
ISABEL MARÍA CARRIÓN MADROÑAL, RAQUEL SÁNCHEZ DEL MORAL, JOSÉ MIGUEL ABAD ZAMORA, FRANCISCO JAVIER MARTÍNEZ MARCOS
http://www.doi.org/10.37201/req/087.2019
LETTER TO THE EDITOR
Rev Esp Quimioter 2020; 33(2): 147-148 [Texto completo PDF]
(Hemofagoctic sindrome by Leishmania in patient with poliglandular sindrome)
ROCÍO CABRA RODRÍGUEZ, MARÍA JOSÉ RUÍZ MÁRQUEZ
http://www.doi.org/10.37201/req/083.2019
LETTER TO THE EDITOR
Rev Esp Quimioter 2020; 33(2): 145-146 [Texto completo PDF]
