Rev Esp Quimioter 2017; 30(6): 464-467

Performance of the KAtex test in screening and diagnosis for visceral leishmaniasis in a reference hospital

CONCEPCIÓN FERNÁNDEZ-ROLDÁN, JAVIER RODRÍGUEZ-GRANGÉR, ROSARIO JAVIER MARTÍNEZ, MIGUEL ÁNGEL LÓPEZ-RUZ, JOSÉ MARÍA NAVARRO-MARÍ, JOSÉ GUTIÉRREZ-FERNÁNDEZ

Introduction. Performing of diagnostic test simple using samples not invasive in the diagnosis of visceral leishmaniasis (VL) may be very beneficial, being necessary comparing to traditional methods.  The objective of this study was to know the reliability of test KAtex in the urine of patients with suspicion of VL.
Material and methods. Retrospectively were reviewed the medical histories of patients with suspected of VL to which are performed the test between 2009 and 2015. For its analysis were selected the patients to which is them had made study of the parasite in bone marrow.
Results. A total of 110 patients were studied, and bone marrow biopsy for research of Leishmania was performed in 44 (40%). In these patients the sensitivity of the test was 50%, the specificity of 96.7%, positive predictive value of 87.5% and negative predictive value of 80.5%.
Conclusions. KAtex antigenuria sensitivity is too low recommending it as a unique method in the detection of VL in our medium.

Rev Esp Quimioter 2017; 30(6): 464-467 [Texto completo PDF]