Rev Esp Quimioter 2022;35(Suppl.3):102-107

Timing in antibiotic therapy: when and how to start, de-escalate and stop antibiotic therapy. Proposals from a stablished antimicrobial stewardship program

JUAN PASQUAU-LIAÑO, SVETLANA SADYRBAEVA-DOLGOVA, SERGIO SEQUERA-ARQUELLADA, CORAL GARCÍA-VALLECILLOS, CARMEN HIDALGO-TENORIO

Published: 24 October 2022

http://www.doi.org/10.37201/req/s03.22.2022

The current morbimortality of serious infections is unacceptable and there is a need to promote the increase in the efficacy of empirical and targeted antibiotherapy. This could be achieved by initiatives coming from ASP teams aimed at promoting increased efficacy of antibiotic therapy .In the optimization of the antibiotic therapy there are several critical points in which an adequate timing could achieve benefits in the survival of patients with severe infections: prompt initiation of empirical treatment; de-escalation performance, appropriate targeted treatment; and finally, curtail antibiotic duration.

Rev Esp Quimioter 2022; 35(Suppl.3):102-107 [Full-text PDF]