Rev Esp Quimioter 2023;36(Suppl.1):9-14

Nosocomial pneumonia: Current etiology and impact on antimicrobial therapy

JULIO JAVIER GAMAZO, FRANCISCO JAVIER CANDEL, JUAN GONZÁLEZ DEL CASTILLO

Published: 24 November 2023

http://www.doi.org/10.37201/req/s01.03.2023

ABSTRACT
Nosocomial pneumonia is an infection with high clinical impact and high morbimortality in which Pseudomonas aeruginosa plays a priority role, especially in the critically ill patient. Conventional antipseudomonal treatments, historically considered as standard, are currently facing important challenges due to the increase of antimicrobial resistance. In recent years, new antimicrobials have been developed with attractive sensitivity profiles and remarkable efficacy in clinical scenarios of nosocomial pneumonia including bacteremia, mechanical ventilation, infections with multidrug-resistant organisms or situations of therapeutic failure. This new evidence underscores the need to update current clinical guidelines for the antimicrobial treatment of nosocomial pneumonia, especially in the most critically ill patients.

Rev Esp Quimioter 2023; 36(Suppl.1):9-14 [Full-text PDF]