Rev Esp Quimioter 2019; 32(3):224-231

Episodes of nontyphoidal salmonellosis in adult patients of the Valladolid West Area in 2017: Evaluation of the suitability of the microbiological culture request and the prescribed treatment

MÓNICA DE FRUTOS, RICARDO MEDINA, ROSA ARAGÓN, LUIS LÓPEZ-URRUTIA, MANUEL GONZÁLEZ-SAGRADO, CARMEN RAMOS, MARTA DOMÍNGUEZ-GIL, SONSOLES GARCINUÑO, LOURDES VIÑUELA, JOSÉ MARÍA EIROS

Introduction. Gastroenteritic salmonellosis is still the second cause diagnosed of infectious diarrhea, most of these clinical pictures are mild and self-limited and therefore the use of antibiotics is limited to few cases. The aim of the study was to describe the episodes of diarrhea caused by Salmonella enterica subsp. enterica, assessing the suitability of the request and the use of antibiotics according to the criteria included in the methodology.
Material and methods. A retrospective, descriptive, observational study was conducted, collecting data from the clinical history.
Results. A total of 122 episodes were included. The reason for consultation was diarrhea, which generated a greater demand in the Hospital Emergency Services (42.6%). The most frequent serotypes isolated were Enteritidis (53.3%), and Typhimurium (40.2%). The adequate request of the stool was 90.2%. Antibiotic was prescribed in 64.6% (79) of the episodes, most patients under 65 years (58 episodes), the average age was 48.43 years. They were treated mainly with ciprofloxacin and azithromycin, in 57 and 14 episodes, respectively. The average duration of antibiotic treatment was 6 days. There was an adequate use of antibiotics in 49.1% of episodes. When the origin of the request was the Hospital Emergency Service, it was inadequate in 63.5% (33) of them. It was inadequate in 60.0% (39) of episodes when ser. Enteritidis was isolated. Almost half, 48.85% (42) of the 58 episodes in which antibiotics were prescribed among those under 65 (86), were treated without being indicated.
Conclusions. Training actions should be implemented focused on optimizing the management of antibiotics in this entity.

Rev Esp Quimioter 2019; 32(3):224-231 [Texto completo PDF]