Rev Esp Quimioter 2017, Feb 11
Prevalence of human papilloma virus in women in a population screening program
JOSÉ Mª EIROS, MÓNICA DE FRUTOS, LUIS LÓPEZ-URRUTIA, LOURDES VIÑUELA, CARMEN RAMOS, JOSÉ Mª JIMÉNEZ
Introduction. The human papillomavirus (HPV), is necesary to cause a woman developing cervical cancer. The aim of the study is to estimate the prevalence of women with HPV infection, belonging to the program of prevention and early detection of cervical cancer of Castilla y León (Spain).
Material and methods. Samples of women included in the screening program were analyzed. Including a total of 120,326 cervical swab samples, collected in the period from January 2012 to December 2014.
Results. A total of 12,183 positive samples were obtained, showing a prevalence of 9.6 ‰, in the female population, with 95.0% confidence interval (CI) between 9.48 and 9.82. The prevalence undergoes a linear decrease with increasing age of women. And by studying the prevalence of different genotypes depending on the risk of cell transformation it is higher in high-risk genotypes at low risk.
Conclusions. The screening system for cervical cancer in Castilla y León is the only screening program implemented in Spain, including the detection of HPV, so that the study results are of great significance for future studies of prevalence of infection and evolution.
Rev Esp Quimioter 2017; Feb 11 [pdf]