Rev Esp Quimioter 2022; 35(6):538-543
Evaluation of two immunocromatographic tests for the detection of antibodies against SARS-CoV-2
SARA MEDRANO, MERCEDES MARTÍNEZ-RODRÍGUEZ, LUIS VALLEJO, ESTHER CULEBRAS, ALBERTO DELGADO-IRIBARREN
Published: 27 September 2022
Introduction. Serological tests have been a valuable tool during the SARS-CoV-2 pandemic, supporting molecular methods for detection, and monitoring the immune response, caused by vaccination or by natural infection. Within all these techniques, rapid tests are interesting due to their ease of use, rapid response and low cost.
Methods. Two different immunological techniques were evaluated: Realy Tech and Mikrogen Diagnostik recomLine SARS-CoV-2 IgG. SARS-CoV-2 IgG II Quant antibody test and SARS-CoV-IgG assay, both from Abbott Diagnostics, were used as reference techniques.
Results. Mikrogen Diagnostik recomLine SARS-CoV-2 IgG shows the best results (S=0.985; E=0.839). Three techniques offered good positive predictive values, but Realy Tech and Healgen negative predictive values left to be desired.
Conclusions. Mikrogen Diagnostik recomLine SARS-CoV-2 IgG showed good results in the detection of antibodies against SARS-CoV-2 and could be used as an alternative to automated techniques.
Rev Esp Quimioter 2022; 35(6):538-543 [Texto completo PDF]