Rev Esp Quimioter 2019; 32(Suppl. 2):32-34

Antibiotic selection in the treatment of acute invasive infections by Pseudomonas aeruginosa  

CELIA CARDOZO, VERÓNICA RICO, DAIANA AGÜERO, ALEX SORIANO

Pseudomonas aeruginosa is characterized by an important intrinsic resistance to antibiotics and it possess an extraordinary ability to develop resistance to nearly all available antimicrobials through selection of mutations. We review some of the pharmacodynamic principles of antibiotics predicting efficacy, clinical experience with monotherapy and combination therapy, and principles for antibiotic treatment for empirical and directed treatment of P. aeruginosa invasive infections.

Rev Esp Quimioter 2019; 32(Suppl. 2):32-34 [Full-text PDF]