Evaluation of pharmacodynamic target attainment with vancomycin treatment of bacteremia due to Staphylococcus aureus methicillin resistant J. A. LEPE, M. V. GIL-NAVARRO, M. D. SANTOS-RUBIO, J. BAUTISTA, J. AZNAR Objective: The objective of the study is to evaluate the ability of standard vancomycin dosing strategies actually recommended to attain the pharmacodynamic target of an […]
Differences in the use of tigecycline between ICU patients and non-ICU patients F. ALVÁREZ-LERMA, L. BLANCO, J.A. RODRÍGUEZ, S. GRAU, D. CONDE-ESTÉVEZ, S. LUQUE Background. Tigecycline is a new broad spectrum antibiotic that is predominantly used for the treatment of severe infections both in critically ill patients admitted to the ICU and in non-ICU […]
The microbiologist and the catheter related infection J. GARCÍA-RODRÍGUEZ, M. DE PABLOS, A. GUTIÉRREZ Different multicentre epidemiological studies such as ENVIN-HELICS or EPINE, have remarked that catheter related bloodstream infection (CRBI) is an increasingly condition in hospital environment. The microbiologist plays a major role in the diagnosis, either by recommending what type of catheter […]
Cefditoren versus ceftazidime in inducer-substrate combinations for the evaluation of AmpC production in a disc approximation test F. CAFINI, L. AGUILAR, L. ALOU, M. J. GIMÉNEZ, D. SEVILLANO, M. TORRICO, N. GONZÁLEZ, P. CORONEL, J. PRIETO Objective: To evaluate cefditoren in inducer-substrate combinations to screen for AmpC induction. Methods: 100 clinical isolates (25 P. […]
Variability in the sensitivity to tigecycline against Acinetobacter baumannii in different culture medium A. TENORIO-ABREU, J. M. EIROS, E. RODRÍGUEZ-MOLINS, D. ANDALUZ, F. BOBILLO, M. DOMÍNGUEZ-GIL, R. ORTIZ DE LEJARAZU Introduction. The tigecycline may represent a therapeutic alternative for the control of multiresistant A. baumannii, although there is no consensus regarding the cutoff points […]
Activity of daptomycin, ciprofloxacin, clindamycin and cotrimoxazole against coagulase-negative Staphylococcus strains with diminished susceptibility to vancomycin M. FAJARDO, R. HIDALGO, S. RODRÍGUEZ, E. GARDUNO, F. F. RODRÍGUEZ, M. ROBLES Introduction. Coagulase Negative Staphylococci (CNS) have become one of the most common nosocomial pathogens and it has a high mortality rate due to the increased […]
Comparative study of the susceptibility to daptomycin and other antimicrobials against Staphylococcus spp. resistant to methicillin and Enterococcus spp. using Wider, E-test, and microdilution methods J. L. GÓMEZ-GARCÉS, F. LÓPEZ-FABAL, A. BURILLO, Y. GIL The human and material costs of inappropriate antimicrobial therapy are high. This study was designed to search for a rapid, […]
Epidemiology and clinical presentation of Panton-Valentin leukocidin positive methicillin-resistant Staphylococcus aureus N. COBOS-TRIGUEROS, C. PITART, F. MARCO, J. A. MARTÍNEZ, M. ALMELA, J. LÓPEZ, M. ORTEGA, A. SORIANO, J. MENSA Introduction: the aim of our study was to review the epidemiology and clinical manifestations of infections due to Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus (PVL-MRSA). […]
A combination of tigecycline, colistin, and meropenem against multidrug-resistant Acinetobacter baumannii bacteremia in a renal transplant recipient: pharmacodynamic and microbiological aspects F.J. CANDEL, N. CALVO, J. HEAD, A. SÁNCHEZ, M. MATESANZ, E. CULEBRAS, A. BARRIENTOS, J. PICAZO Acinetobacter baumannii are emerging as the causal agents of healthcare-associated infections. We describe a renal transplant recipient […]
Treatment of human infections caused by Bartonella spp. L. PÉREZ-MARTÍNEZ, J. R. BLANCO, J. A. OTEO Infections by Bartonella spp. include a wide spectrum of emerging and re-emerging infectious diseases.There is not a universal therapy for this infection, therefore treatment should be chosen individually. The aim of this review is to update the therapeutics […]
