Rev Esp Quimioter 2024; 37(2): 127-133
Safety of fluoroquinolones
JOSÉ BARBERÁN, ALICIA DE LA CUERDA, MARÍA ISABEL TEJEDA GONZÁLEZ, ANA LÓPEZ APARICIO, CARLOS MONFORT VINUESA, ALEJANDRO RAMOS SÁNCHEZ, LOURDES CRISTINA BARBERÁN
Published: 22 December 2023
http://www.doi.org/10.37201/req/143.2023
Fluoroquinolones (FQs) are one of the most commonly prescribed classes of antibiotics. Although they were initially well tolerated in randomized clinical trials, subsequent epidemiological studies have reported an increased risk of threatening, severe, long-lasting, disabling and irreversible adverse effects (AEs), related to neurotoxicity and collagen degradation, such as tendonitis, Achilles tendon rupture, aortic aneurysm, and retinal detachment. This article reviews the main potentially threatening AEs, the alarms issued by regulatory agencies and therapeutic alternatives.
Rev Esp Quimioter 2024; 37(2): 127-133 [Full-text PDF] [Texto completo PDF]
