Rev Esp Quimioter 2022; 35(1):43-49

Sepsis Code: dodging mortality in a tertiary hospital

ROSA MÉNDEZ, ANGELS FIGUEROLA, MARTA CHICOT, ANA BARRIOS, NATALIA PASCUAL, FERNANDO RAMASCO, DIEGO RODRÍGUEZ, ÍÑIGO GARCÍA, ANDRÉS VON WERNITZ, NELLY ZURITA, AUXILIADORA SEMIGLIA, DAVID JIMÉNEZ, SARA NAVARRO, MARÍA JOSÉ RUBIO, MERCEDES VINUESA, LOURDES DEL CAMPO, AZUCENA BAUTISTA, ALBERTO PIZARRO

Published: 23 November 2021

http://www.doi.org/10.37201/req/105.2021

Background. In the hospital of La Princesa, the “Sepsis Code” (CSP) began in 2015, as a multidisciplinary group that provides health personnel with clinical, analytical and organizational tools, with the aim of the detection and early treatment of patients with sepsis. The objective of this study is to evaluate the impact of CSP implantation on mortality and to determine the variables associated with an increase in it.
Material and methods. A retrospective analytical study of patients with CSP alert activation from 2015 to 2018 was conducted. Clinical-epidemiological variables, analytical parameters, and severity factors such as admission to critical care units (UCC) and the need for amines were collected. Statistical significance was established at p < 0.05.
Results. We included 1,121 patients. The length of stay was 16 days and 32% required admission to UCC. Mortality showed a statistically significant linear downward trend from 24% in 2015 to 15% in 2018. The predictive mortality variables with statistically significant association were lactate > 2 mmol/L, creatinine > 1.6 mg/dL and the need for amines.
Conclusions. The implementation of Sepsis Code decreases the mortality of patients with sepsis and septic shock. The presence of a lactate > 2 mmol/L, creatinine > 1.6 mg/dL and/or the need to administer amines in the first 24 hours, are associated with an increase in mortality in the patient with sepsis.

Rev Esp Quimioter 2022; 35(1):43-49 [Texto completo PDF]