Investigation of antimicrobial resistance to Enterococcus faecium M. M. CASAL, M. CAUSSE, F. SOLÍS, F. RODRÍGUEZ-LÓPEZ, M. CASAL We performed a antibiotic resistance study on Enterococcus faecium isolated from intrahospitalary and extrahospitalary samples between 2004 and 2010. Three different samples were studied; urine, blood and wound swabs, considering a strain per patient. We included in […]
Matematical modeling of antibiotic resistance. Perspectives from a meta-analysys M. J. FRESNADILLO-MARTÍNEZ, E. GARCÍA-SÁNCHEZ, E. GARCÍA-MERINO, Á. MARTÍN-DEL-REY, Á. RODRÍGUEZ-ENCINAS, G. RODRÍGUEZ-SÁNCHEZ, J. E. GARCÍA-SÁNCHEZ The antibiotic resistance is one of the greatest challenges of the international health community. The study of antibiotic resistance must be a multidisciplinary task and, in this sense, the main […]
Pneumococcal bacteremia in adult patients at a hospital in Madrid: serotypes and susceptibility M. CORREA, J. C. SANZ, C. DE LAS CUEVAS, A. GUIU, D. DOMINGO, T. ALARCÓN, M. LÓPEZ-BREA Introduction. The aim of this study is to describe the distribution of Streptococcus pneumoniae serotypes, its antimicrobial susceptibility profiles and the relation with vaccines in […]
Prospective comparison of severity scores for predicting mortality in community-acquired pneumonia S. LUQUE, J. GEA, P. SABALLS, O. FERRÁNDEZ, N. BERENGUER, S. GRAU Introduction. Specific prognostic models for communityacquired pneumonia (CAP) to guide treatment decisions have been developed, such us the Pneumonia Severity Index (PSI) and the Confusion, Urea nitrogen, Respiratory rate, Blood pressure and […]
Antibiotic prescribing to the paediatric population of Castilla y León in the last decade: trends, seasonal fluctuations and geographical differences M. E. VÁZQUEZ, J. M. EIROS, F. MARTÍN, S. GARCÍA, R. M. BACHILLER, M. J. VÁZQUEZ Introduction. The development of antibiotic resistance is a danger to the health of the population, especially for children, due […]
Rifampin breakpoint for Acinetobacter baumannii based on pharmacokinetic-pharmacodynamic models with Monte Carlo simulation J. A LEPE, E. GARCÍA-CABRERA, M.V. GIL-NAVARRO, J. AZNAR Objective: The aim of this study is to develop a pharmacokinetic–pharmacodynamic (PK–PD) rifampin breakpoint for Acinetobacter baumannii based on Monte Carlo simulation and to compare it with the reference value establish by the […]
Peripheral venous catheter-related bacteremia in a general hospital M. DELGADO-CAPEL, A. GABILLO, L. ELIAS, J. C. YÉBENES, G. SAUCA, J. A. CAPDEVILA Introduction. Catheter sepsis is a constant and serious problem in our hospitals for the cost it generates, both in terms of morbidity and economics. It’s becoming more frequent also in peripherally inserted catheters. Our […]
Plasmid-mediated AMPc producing Proteus mirabilis in the Health Care Area of Santiago de Compostela: molecular and epidemiological analysis by rep-PCR and MALDI-TOF M. TREVIÑO, D. NAVARRO, G. BARBEITO, P. ARESES, C. GARCÍA-RIESTRA, B. J. REGUEIRO Introduction: Proteus mirabilis is an important pathogen isolated from both community-acquired and health-care associated infections. Acquired AmpC-type beta-lactamases represent an important […]
Antibiotheraphy in the 21st century, antibacterials for the second decade. Posibilities or realities in the future? J. E. GARCÍA-SÁNCHEZ, E. GARCÍA-MERINO, Á. MARTÍN-DEL-REY, E. GARCÍA-SÁNCHEZ A review of some antibacterial products is done motivated by the serious situation arisen by the antimicrobial resistance in bacteria. The attention is focus on those drugs with suitable antimicrobial properties […]
Emergence of plasmid mediated AmpC β-lactamasas: Origin, importance, detection and therapeutical options C. SERAL, M. J GUDE, F. J. CASTILLO AmpC β-lactamases can hydrolyze penicillins, oxyimino-, 7-α-methoxycephalosporins and monobactams. Susceptibility to cefepime or cefpirome is little affected and is unchanged for carbapenems. Originally such genes are thought to have been mobilized to mobile genetic elements […]
